ʻO ka pauka Phlorizin

He aha ka pauka Phlorizin?

ʻO ka pauka Phlorizin, i kapa ʻia ʻo phloridzin, he pūhui glycoside i hana ʻia e ka hui ʻana o phloretin a me kahi mole glycoside, nona ka subclass flavonoid o dihydrochalcones. 

He mea phenolic ia i unuhi ʻia mai nā ʻāpala, nā ʻili ʻōpala, nā lau, a me nā ʻāpana ʻē aʻe. ʻO kekahi o kāna huahana degradation, phloretin, e hōʻike ana i ka pale ʻana i ka hana microbial. He mea ʻokoʻa kona hōʻiliʻili ʻana i nā mea kanu o ka ʻano Malus, i unuhi mua ʻia mai ka ʻili aʻa o nā ʻāpala (Malus domestica). ʻOi aku ka kiʻekiʻe o kāna mea i loko o ka peel (mai ka 12 a 418 mg / kg) ma mua o ka mea i loaʻa i nā ʻano like ʻole o ka pulp (4 a 20 mg / kg).

ʻO Yuantai Organic Testing:

Ua hōʻoia piha ʻia e hoʻokō i nā koi nānā maikaʻi o nā ʻāina like ʻole. Ke hoʻohana nei i kahi ʻano High-Performance Liquid Chromatography (HPLC) i hui pū ʻia me kahi Evaporative Light Scattering Detector (ELSD) a i ʻole kahi Diode Array Detector (DAD), hiki iā mākou ke ʻike maikaʻi a pololei i nā loli i ka ʻike phlorizin i loko o nā laʻana.

ʻO nā mea koʻikoʻi o ka HPLC assay nā: 

• E hōʻoia ana i ka nui o ka laʻana ma mua o 0.2g a i ʻole 0.2mL.

• Kaapuni: 2 a 3 pule.

• Ma hope o ka pau ʻana o ka papahana, e hāʻawi mākou i kahi hōʻike ʻenehana kikoʻī, e pili ana:

1. Nā kaʻina hana hoʻokolohua.

2. Nā ʻāpana spectrometry nuipaʻa pili.

3. Nā kiʻi spectrometry lehulehu.

4. ʻIke maka.

5. ʻO ka ʻike maʻiʻo Phlorizin.

Nā mea koʻikoʻi no ka noiʻi:

1. Hoʻopau ka PHZ i ka momona i hoʻoulu ʻia e ka meaʻai momona momona (HFD).

2. Hoʻemi ʻo PHZ i ka microbiota a me nā pilikia metabolic i hoʻoulu ʻia e ka meaʻai momona momona (HFD).

3. Ho'ēmi ka PHZ i ka pōʻino o ka ʻōpū ma muli o ka ʻai momona momona (HFD).

ʻO ka pilina ma waena o ka ʻāpana microbial taxa a me nā metabolites (nā ʻakika momona pōkole, SCFA, a me lipopolysaccharides, LPS).

4. ʻO ka hoʻololi ʻana i nā ʻiole fecal mai ka phlorizin (PHZ) i mālama ʻia e hoʻēmi i ka momona a me ka pōʻino o ka ʻōpū i hoʻoulu ʻia e ka meaʻai momona momona (HFD).

5. Hōʻike hoʻolālā e hōʻike ana i nā hana kūpono o ka phlorizin (PHZ) anti-metabolic disorder (MD) hopena.

ʻO ka hana o ka pauka Phlorizin:

1. Ka hopena i ke koko glucose a me nā lipids: Hiki i ka nui o ka phlorizin ke alakaʻi i ka glucosuria. Hoʻemi ia i ka lawe ʻana o ka glucose i loko o ka ʻōpū liʻiliʻi a hoʻonui i ka hoʻokuʻu ʻana o ka glucose renal, me ka hoʻohaʻahaʻa pono i nā pae glucose koko. Hoʻoikaika ia i ka huna ʻana o ka glucose, hoʻohaʻahaʻa i ka hoʻokē ʻai a me ka pae koko ma hope o ka ʻai me ka ʻole o ka hopena hypoglycemic. ʻO ka mālama ʻana i nā ʻiole diabetic me ka phlorizin e hoʻihoʻi i ka ʻike insulin i nā pae maʻamau. Hōʻike pū ia i nā hopena hoʻohaʻahaʻa lipid.

2. Hoʻonui i ka naʻau: Hōʻike ka noiʻi e hoʻonui ka phlorizin i ka hoʻomanaʻo. Hoʻonui ia i ke aʻo ʻana a me ka hoʻomanaʻo ʻana i nā rodents a kūʻē i ka hōʻino hoʻomanaʻo i ka insulin. He nui nā lāʻau lapaʻau e hoʻonui i ka hoʻomanaʻo ʻana ma o ka hoʻololi ʻana i nā pae glucose kaiapuni, akā ke keʻakeʻa nei ia i ke komo ʻana o ka glucose i loko o ka lolo. ʻO kāna hana no ka hoʻonui ʻana i ka hoʻomanaʻo ʻana i ka lolo me he mea lā e hana kūʻokoʻa i nā pae glucose koko a i ʻole hiki i ka lolo glucose absorption capacity.

3. Nā Pono Antioxidant: he glycoside derivative o dihydrochalcone phloretin, me nā ʻano antioxidant kaulana. ʻOi aku ka nui o kona mana antioxidant ma mua o ka huaora C a me ka huaora E, me kahi hana antioxidant kūʻokoʻa. Eia kekahi, hiki ke hydrolyzed in vivo e hana i ka phloretin, e hōʻike ana i nā mana antioxidant kiʻekiʻe.

noi:

No ka Phlorizin i ka subclass dihydrochalcone o nā mea kanu flavonoids. hōʻike ia i nā hana olaola like ʻole, e like me ke kahe koko a me ka hoʻoponopono koko glucose, pale puʻuwai, a me ka scavenging o nā radical manuahi. ʻO ka mea nui, loaʻa iā ia ka haʻahaʻa haʻahaʻa a loaʻa i nā noi ākea i nā kahua he nui:

1. Lapaʻau: ʻO ka pauka Phlorizin kaohi i ka glucose reabsorption i loko o ka renal proximal tubule, e alakaʻi ana i ka hoʻonui ʻana i ka urine glucose excretion a hoʻemi i ke kiʻekiʻe o ka glucose koko, me ka ʻole o ka pili ʻana i ka pae o ka insulin serum.

2. Nā mea hoʻonani: hiki ke hoʻohana ʻia ka Phlorizin no ka hoʻomaʻemaʻe ʻana i ka ʻili a me ka mālama ʻana i ka haki. Kāohi ia i ke komo ʻana o ka glucose i loko o nā cell epidermal, hoʻolohi i ka huna ʻana o ka sebum a kōkua i ka pale ʻana i ka haki. Ma ke kāohi ʻana i ka tyrosinase, kahi enzyme nui i ka biosynthesis melanin, hāʻawi ka phlorizin i ka keʻokeʻo ʻili.

3. Meaʻai: Hōʻike pū ʻo Phlorizin i nā waiwai antioxidant.

palapala

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ʻO kā mākou hui a me ka hale hana

Nā hōʻailona wela: Phlorizin Powder, Mea kūʻai, mea hana, hale hana, kūʻai, kumukūʻai, no ke kūʻai aku, mea hana, hāpana manuahi, OEM, ODM, lepili pilikino, lepili keʻokeʻo.